Methyl-group Specific Predictor 1.0

Methyl-group Specific Predictor is a computational tool developed by The CUCKOO Workgroup to identify and prioritize methylation sites with residue- and context-specific detail across biomolecules. It leverages curated data and modern machine learning to analyze sequence and other relevant features, helping researchers pinpoint likely methylation events and differentiate among methylation types. The software is designed for both exploratory studies and high-throughput pipelines, offering clear confidence scores and exportable results to streamline downstream analysis.

Key capabilities:

• Predicts methylation sites with methyl-group specificity on biological sequences
• Provides interpretable scores and confidence estimates for each predicted site
• Supports interactive use and batch processing for large datasets
• Outputs results in standard, analysis-ready formats
• Includes documentation and example workflows to accelerate onboarding

Use cases include epigenetics, proteomics, functional annotation, and target selection for experimental validation. By focusing on methyl-group–specific patterns, the tool helps reduce experimental burden, prioritize hypotheses, and improve the reproducibility of methylation research across diverse organisms and data types.

Methyl-group Specific Predictor is developed by The CUCKOO Workgroup. The most popular version of this product among our users is 1.0. The name of the program executable file is GPS-MSP.exe.